Bonds in Antigen-Antibody Reaction

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Chemical bonds in Antigen-Antibody Reactions

The antigen- antibody interaction is bimolecular irreversible association between antigen and antibody. The association between antigen and antibody includes various non-covalent interactions between epitope (antigenic determinant) and variable region (VH/VL) domain of antibody in a similar manner to that in which proteins bind to their cellular receptors, or enzymes bind to their substrates.